The teams looking to win their third straight game matchup when the Kansas City Chiefs take on the Jacksonville Jaguars on “Monday Night Football.” Kansas City is coming off a 37-20 victory over the Baltimore Ravens, while Jacksonville took down San Francisco 26-21 in Week 4. The Chiefs (2-2), who are 1-1 against AFC foes, are also 1-1 on the road this season. The Jaguars (3-1), who are 1-1 in the conference, are 2-0 on their home field in 2025.
Kickoff from Everbank Stadium in Jacksonville, Florida is scheduled for 8:15 p.m. ET. Kansas City leads the all-time series 10-6, with the Chiefs winning each of the last eight meetings. Kansas City is a 3.5-point favorite in the latest leads against the Jaguars from The Sportsline, down from the opener, while the over/under for total points scored is 45.5, down from the opener. Kansas City is a -198 moneyline favorite (risk $198 to win $100), while Jacksonville is a +165 underdog (risk $100 to win $165). Before you make any Chiefs vs. Jaguars picks, be sure to see what Sportsline expert Mike Tierney has to say.
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A veteran sportswriter whose work appears periodically in the New York Times and the Los Angeles Times, Mike Tierney has covered the NFL for decades and reported on seven Super Bowls. He is 235-189-13 in his NFL picks the last three seasons, returning $2,505 to $100 (each BET 1 unit). He hit on 61.2% of his ATS picks (61-39-3) last season. Tierney is also 33-17-1 (+1461) in his last 51 picks in the Jacksonville Jaguars Games. Anyone following could have seen huge returns.
Now, Tierney has cast his sights on the Chiefs against the Jaguars and has just locked in his picks and predictions. You can head to Sportsline now to see his picks. Here are several NFL odds and NFL Betting Lines for Jaguars vs. Chiefs:
Chiefs vs Jaguars spread | Kansas City -3.5 at DraftKings Sportsbook |
Chiefs vs. Jaguars Over/Un | 45.5 points |
Chiefs money line vs. Jaguars | Kansas City -198, Jacksonville +165 |
Chiefs vs. Jaguars | See the picks at SportsLine |
Chiefs vs. Jaguars streaming | Fubo (try for free) |
Patrick Mahomes continues to be the difference maker in the Kansas City offense. In four games this season, he completed 87 of 142 passes (61.3%) for 939 yards and seven touchdowns with one interception for a rating of 94.2. He also leads the Chiefs in rushing, carrying 22 times for 130 yards and two touchdowns, with an explosive 22-yard play and 10 conversions in the first. In the victory over the Ravens, he completed 25 of 37 passes (67.6%) for 270 yards and four touchdowns.
Among his more explosive weapons on offense was fourth-year veteran Tyquan Thornton. The 25-year-old only has 10 receptions this season, but he has 182 receiving yards with three touchdowns. He has scored a touchdown in each of the last three games. In a 22–9 victory over the New York Giants on September 21, he caught a game-high five passes for 71 yards and a score. See which team returns at Sportsline.
Fifth-year veteran quarterback Trevor Lawrence Keys attacks the Jaguars. The top pick in the 2021 NFL Draft by Jacksonville completed 58.3% of his passes for 845 yards and five touchdowns with four interceptions. In a 31–27 loss at Cincinnati on September 14, he completed 24 of 42 passes for 271 yards and three touchdowns with two interceptions. In last week’s win at San Francisco, he completed 21 of 31 passes (67.7%) for 174 yards and a touchdown.
Running back Travis Etienne Jr. fuels Jacksonville’s ground attack. The fifth-year veteran rushed 65 times for 394 yards (6.1 average) and two touchdowns. He had three explosive plays of 20 yards or more, including a long one of 71, with 13 first-down conversions. He also had six receptions for 32 yards and a score. In the victory over the 49ers, he carried 19 times for 124 yards and a touchdown. See which team returns at Sportsline.
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Tierney analyzed the Chiefs against the Jaguars from all angles and he’s looking at the point total. He also discovered a critical X-factor that causes him to jump to one side of the spread. He’s only sharing what he’s on, and what side, at Sportsline.
Who wins the Chiefs against the Jaguars, and which X-Factor review makes one side of the spread a must-watch?. You can head to Sportsline to watch its Chiefs vs. Jaguars. Visit Sportsline now to see which side you should jump to, all from the expert who is 33-17-1 over his last 51 Jacksonville Jaguars picks, and find out.
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